Changes in Total Tear Protein and Lipocalin Concentration According to Frequency of Artificial Tear Usage
نویسندگان
چکیده
منابع مشابه
Decreased tear lipocalin concentration in patients with meibomian gland dysfunction.
BACKGROUND/AIM Recent studies have demonstrated that tear lipocalin (TL) and phospholipids have a crucial role in maintaining tear film stability. The level of TL in patients with meibomian gland dysfunction (MGD) was examined and these data were correlated with the severity of their clinical disorder. METHODS 12 patients with obstructive MGD, 12 patients with seborrhoeic MGD, and 12 age matc...
متن کاملAdsorption of human tear lipocalin to human meibomian lipid films.
PURPOSE Tear lipocalin (Tlc) is a major lipid binding protein in tears and is thought to have an important role in stabilizing the Meibomian lipid layer by transferring lipids to it from the aqueous layer or ocular surface, or by adsorbing to it directly. These possible roles have been investigated in vitro using human Tlc. METHODS Tlc was purified from human tears by size exclusion chromatog...
متن کاملTear lipocalin, lysozyme and lactoferrin concentrations in postmenopausal women
RATIONALE Among the most frequently encountered pathologies examined by the ophthalmologist is dry eye syndrome (DE), which can be discovered particularly in the elderly. The initial diagnosis of DE is of high importance, but also challenging. This is because the biochemical changes in the tear film often develop before any detectable signs. OBJECTIVE In this study, the possible relationship ...
متن کاملLETTERS TO THE EDITOR Survey of artificial tear and saliva usage among patients with Sjögren’s syndrome
Sjögren’s syndrome (SS), a chronic immune mediated disease associated with xerostomia and keratoconjunctivitis sicca, may occur alone (primary SS) or with other autoimmune diseases (secondary SS). The benefits of substitution treatment for dry eyes and mouth seem very variable. This survey assessed patients’ experience of the wide variety of tear and saliva substitutes available. Patients with ...
متن کاملInteraction of tear lipocalin with lysozyme and lactoferrin.
The interaction of human tear lipocalin with lysozyme and lactoferrin was studied by electron paramagnetic resonance (EPR) spectroscopy. TL mutants I98C and F99C were spin labeled with MTSL and its derivative. The spectra demonstrated that at sites C98 and C99 the mobility of the nitroxides was reduced in the presence of lysozyme, lactoferrin, but not albumin. The reduced mobility was manifeste...
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ژورنال
عنوان ژورنال: Journal of the Korean Ophthalmological Society
سال: 2019
ISSN: 0378-6471,2092-9374
DOI: 10.3341/jkos.2019.60.5.414